We will continue to monitor and revise this article as new literature is published on cataplexy.Ĭataplexy is a sudden muscle weakness that occurs while a person is awake. Dosage reduction is recommended in patients known to be poor CYP2D6 metabolizers these patients have higher concentrations of WAKIX than normal CYP2D6 metabolizers.Our medical review team has recently evaluated this page to ensure accuracy.Dosage adjustment of WAKIX is recommended in patients with moderate or severe renal impairment. WAKIX is not recommended in patients with end-stage renal disease.Dosage adjustment is required in patients with moderate hepatic impairment. WAKIX is contraindicated in patients with severe hepatic impairment. WAKIX is extensively metabolized by the liver.The safety and effectiveness of WAKIX have not been established in patients less than 18 years of age.To enroll or obtain information from the registry, patients can call 1-80. Patients should be encouraged to enroll in the WAKIX pregnancy registry if they become pregnant. There is a pregnancy exposure registry that monitors pregnancy outcomes in women who are exposed to WAKIX during pregnancy.Patients using hormonal contraception should be advised to use an alternative non-hormonal contraceptive method during treatment with WAKIX and for at least 21 days after discontinuing treatment. WAKIX may reduce the effectiveness of hormonal contraceptives.The effectiveness of hormonal contraceptives may be reduced when used with WAKIX and effectiveness may be reduced for 21 days after discontinuation of therapy. Therefore, reduced effectiveness of sensitive CYP3A4 substrates may occur when used concomitantly with WAKIX. WAKIX is a borderline/weak inducer of CYP3A4.Patients should avoid centrally acting H 1 receptor antagonists. H 1 receptor antagonists that cross the blood-brain barrier may reduce the effectiveness of WAKIX.Dosage adjustments may be required (see full prescribing information). Concomitant use of WAKIX with strong CYP3A4 inducers decreases exposure of pitolisant by 50%.Concomitant administration of WAKIX with strong CYP2D6 inhibitors increases pitolisant exposure by 2.2-fold.Other adverse reactions that occurred at ≥2% and more frequently than in patients treated with placebo included headache, upper respiratory infection, musculoskeletal pain, heart rate increased, hallucinations, irritability, abdominal pain, sleep disturbance, decreased appetite, cataplexy, dry mouth, and rash. In the placebo-controlled clinical trials conducted in patients with narcolepsy with or without cataplexy, the most common adverse reactions (≥5% and twice placebo) for WAKIX were insomnia (6%), nausea (6%), and anxiety (5%).WAKIX is not recommended in patients with end-stage renal disease (ESRD). Dosage modification is recommended in patients with moderate hepatic impairment and moderate or severe renal impairment (see full prescribing information). The risk of QT prolongation may be greater in patients with hepatic or renal impairment due to higher concentrations of pitolisant monitor these patients for increased QTc.Avoid use in patients with a history of cardiac arrhythmias, as well as other circumstances that may increase the risk of the occurrence of torsade de pointes or sudden death, including symptomatic bradycardia, hypokalemia or hypomagnesemia, and the presence of congenital prolongation of the QT interval. WAKIX prolongs the QT interval avoid use of WAKIX in patients with known QT prolongation or in combination with other drugs known to prolong the QT interval.WAKIX is also contraindicated in patients with severe hepatic impairment. WAKIX is contraindicated in patients with known hypersensitivity to pitolisant or any component of the formulation.
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DK2: Remember how DK1's editor had all those neat placeables? DK2 doesn't.DK2: It lacked arbitrary hero variety.Why should something that was rapid-fire in DK1's possession mode have a timer in DK2? Same with monster attacks. DK2: I know it's not worth mentioning a counterpoint to one of the "Good" points above, but seriously, DK2 creatures are just too darn slow.Runestone Keeper is due out digitally for Switch via the eShop on August 20. However, Circle Entertainment published a launch trailer for the game today see it below. DK1: The Scavenger Room felt like a gimmick that actually did more harm than good. Runestone Keeper, a challenging roguelike / roguelite dungeon crawler, still has another day to go until release on Switch.If you were lucky, it would disintegrate while an enemy was attempting to claim or cross it. It was actually a tactical advantage to link two areas over lava when you wanted the bridge to disappear, without the additional expense of constructing a stone bridge. Now on Nintendo Switch, Runestone Keeper will keep you coming back for one more floor, one more run, as you try to push through the dangers of the dungeon Heroes, monsters, equipment, events. I really didn't mind that the Wooden bridge disappeared over lava. DK2: The Stone bridge was a nice addition.More of a novelty in DK2, but a functional one. He was a crazy powerful creature in DK1, and an unstoppable puzzle-unlock in DK2. The concept of mana was interesting, though possibly unnecessary.Wish there was a toggle, or a toggle-button to hold so it would work rectangularly. It was locked in rectangular dragging, sure, but that was actually okay. DK2: You could build and dig in rectangular ways.O_O ) and you could build and sell quickly. Creatures attack fast, had more skills, could fire them more quickly, (FAR more quickly. You could slap that creature slot machine in My Pet Dungeon, you could manipulate the casino winning slider, you could slap picropiglets, lock the prison gate, and so on. Creatures had a bubble above their heads that told you what they wanted, and you saw them going for it, as well as the routes they were taking. DK1: Smooth fluidity of the game - There was no lag, no slowness, nothing moving like molasses.I don't remember if I've posted my list in a while, but I'm sure it mimics most of the lists here. If you took the best elements of both games - which is sort of where I'm hoping WftO is going - it would be brilliant. I think my biggest beef with DK2 was not being able to train my creatures to level 10 the training pit was bad enough, but not being able to get to level 10 was just annoying: and I dislike timer missions at the best of times (though I think only DK 2 had them in the main campaign) as I like to spend my time.ĭK 1 I think has the best monster-setup mechanically (more powers, and better - I still swear by Dark Mistress in DK as being the best monster, on account of stats, powers, ease of keeping and above all teleport.) DK 1's main campaign intros and outros were the best, I think, there though. I never completed DK2's main campaign at all, though I fracked about in the pet dungeon a fair bit. Software description provided by the publisher.DK 1 overall, though DK 2 had some good elements (imps levelling via normal tasks, those hilarious comments that would come up abruptly for no reason.) I DK's Deeper Dungeons were the best missions overall - DK's main campaign just nevered seemed quite as good (possibly because you could whiz through about half of it with a send-creature-on when you got a level 10 priestess (which I frequently used, because flight and Horny was to much of a pain to keep around - I almost always ditched them fairly quickly)). Ě Challenging Experience - Prepare to have a tragic (not to mention permanent) death!.Heroes and Goddesses – Create your hero’s attributes build! Sacrifice to receive your mighty God’s blessing (and later betray him to check out his fury)!. Choose wisely and use the unwelcoming surroundings to your advantage!
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BATTLE BEARS: ZOMBIES! apk v1.0.6 for Android But I find it a little more cumbersome to use than I'd like. In the pros and cons at the beginning of this article, I described the software as "clunky." That's a subjective opinion, because the software does all it's supposed to do, and more. That said, since you're probably going to interact a bit more with each scan than you would if you were using a bulk sheet scanner, it's probably not too much of an inconvenience to require a USB connection to the computer. I would have preferred a Wi-Fi or Bluetooth interface. If you see inaccuracies in our content, please report the mistake via this form. If we have made an error or published misleading information, we will correct or clarify the article. Our editors thoroughly review and fact-check every article to ensure that our content meets the highest standards. Our goal is to deliver the most accurate information and the most knowledgeable advice possible in order to help you make smarter buying decisions on tech gear and a wide array of products and services. ZDNET's editorial team writes on behalf of you, our reader. Indeed, we follow strict guidelines that ensure our editorial content is never influenced by advertisers. Neither ZDNET nor the author are compensated for these independent reviews. This helps support our work, but does not affect what we cover or how, and it does not affect the price you pay. When you click through from our site to a retailer and buy a product or service, we may earn affiliate commissions. And we pore over customer reviews to find out what matters to real people who already own and use the products and services we’re assessing. We gather data from the best available sources, including vendor and retailer listings as well as other relevant and independent reviews sites. ZDNET's recommendations are based on many hours of testing, research, and comparison shopping. Open "Abilities" and tap on a power you wish to improve, such as Shield Duration, Coin Magnet, and Boost Distance. Want To Play In Fullscreen : Hold down the CTRL key and scroll the mouse middle button up to zoom in and down to zoom out. How do you power up in Temple Run 2: Frozen Shadows? How far can you get pretty insane running game. What is the power meter in Temple Run 2: Frozen Shadows?Ĭollect coins and fill the power meter in Temple Run 2: Frozen Shadows to unlock a temporary speed and invincibility boost. They chase the player in their quest to retrieve the golden idol. What is the monster in Temple Run 2: Frozen Shadows?Įvil Demon Monkeys (or devil monkey) are the main antagonists of Temple Run and its sequel, Temple Run 2. You need an internet connection to play Temple Run 2: Frozen Shadows on Poki. Is Temple Run 2: Frozen Shadows an online game or an offline game? As the game is an endless running game, there is no end to the temple the player plays until the character collides into a large obstacle, falls into the water, or is overtaken by the demon monkeys. Play as Oz and outrun the shrieking flying baboons as you turn, jump and slide your way across the land. You can play Temple Run 2: Frozen Shadows on your browser without installing or downloading for free on Poki. The most thrilling running experience now comes to the yellow brick road Disney and Imangi Studios present Temple Run: Oz, an endless runner inspired by Temple Run 2 and the film Oz the Great and Powerful. How can I play Temple Run 2: Frozen Shadows on PC? Play their legendary endless runner games Temple Run 2, Temple Run 2: Holi Festival, and Temple Run 2: Jungle Fall on Poki! How do you complete Temple Run 2: Frozen Shadows?Ĭollect free coins, jump a second before you near the edges, upgrade your character stats, time your jumps well over double-jump obstacles, and make sure to complete stage objectives. Temple Run 2: Frozen Shadows is a new map in the second installment of the mega-hit Temple Run. Who created Temple Run 2: Frozen Shadows? Do you dare to join this exciting adrenaline-charged adventure? Watch your step, the ice looks slippery! How to play Temple Run 2: Frozen Shadows online? Keyboard From the icy caves and the narrow ledges of the ravines to the dangerous ice skates, the Frozen Shadows map adds more depth and excitement to the classic Temple Run 2 adventure. The player must escape from her enemy and avoid all the obstacles and traps that are found along the way, and escape with the gold idol. Swipe to turn, jump and slide to avoid obstacles, collect coins and buy power ups, and see how far you can run REVIEWS. Test your reflexes as you race down ancient temple walls and along sheer cliffs. Temple Run 2: Frozen Shadows is an endless runner game developed by Imangi. From the makers of the award-winning best-seller Harbor Master comes the most exhilarating running game on the App Store. In his work on probability Ars Conjectandi, originally published in Latin in 1713, Jakob Bernoulli used the phrase "Ars Conjectandi sive Stochastice", which has been translated to "the art of conjecturing or stochastics". The word stochastic in English was originally used as an adjective with the definition "pertaining to conjecturing", and stemming from a Greek word meaning "to aim at a mark, guess", and the Oxford English Dictionary gives the year 1662 as its earliest occurrence. Stochastic modeling is also used in social science. It is also used in finance, due to seemingly random changes in financial markets as well as in medicine, linguistics, music, media, colour theory, botany, manufacturing, and geomorphology. Stochasticity is used in many different fields, including the natural sciences such as biology, chemistry, ecology, neuroscience, and physics, as well as technology and engineering fields such as image processing, signal processing, information theory, computer science, cryptography, and telecommunications. Furthermore, in probability theory, the formal concept of a stochastic process is also referred to as a random process. Although stochasticity and randomness are distinct in that the former refers to a modeling approach and the latter refers to phenomena themselves, these two terms are often used synonymously. Stochastic (from Greek στόχος (stókhos) 'aim, guess' ) refers to the property of being well described by a random probability distribution. ( January 2020) ( Learn how and when to remove this template message) Please help improve the article by merging similar sections and removing unneeded subheaders. This article may have too many section headers dividing up its content. The modern ubiquity and power of computers lead to the rapid development of computer-aided technologies extensively used in many applications, including but not limited to aerospace, automotive, shipbuilding, building and construction, electricity and electronics, industrial and architectural design, prosthetics, furniture, fashion products, and many more. Michel Biron, in Thermoplastics and Thermoplastic Composites (Third Edition), 2018 8.2.1 Overview Mastercam supports model import directly from Pro/ENGINEER in addition to other CAD systems (e.g., SolidWorks, CATIA, and AutoDesk). Since creating the sculpture surface by blending circular arcs on four parallel planes using Mastercam is more time consuming, we will import the Pro/ENGINEER part of the block into Mastercam. We will create three sequences using Mastercam-surface rough flowline, rough-restmill, and surface finish-which correspond to volume milling, local milling, and contour surface milling in Pro/MFG. This tutorial focuses on using Mastercam to create a similar machining simulation. As discussed in Section 11.3, three NC sequences-volume milling, local milling, and contour surface milling-were employed for machining the surface using Pro/MFG. NC sequences for machining the sculpture surface of the block example discussed in Section 11.3 are chosen as the second tutorial example. Volume CNC sequences for machining a name plate using Mastercam: (a) creating text for volume milling, (b) combined toolpath, and (c) machining simulation. Note that the text engraved will have the same size as the cutter (⅛ in.) that is, the cutter will move one pass along the outer profile of individual letters.įigure 11.41. The same cutter with a step depth, ⅛ in., is chosen for the engraving NC sequence. As shown in Figure 11.40(d), six letters-“Groove”-in an outline style are defined in the design model. The toolpath for the engraving sequence in this example is created using a Groove feature in Pro/ENGINEER. For some intricate surfaces, Pro/MFG may not be able to process the trim function. In using Pro/MFG, creating a mill volume involves making a sketch, extruding the sketch for a solid block, and intersecting the block with the design model to generate a trim solid feature that represents exactly the material to be removed. Note that in creating a volume milling sequence using Pro/MFG, users will have to create a “mill volume,” which defines the portion of the workpiece to be removed. In general, the toolpath generated for volume milling is acceptable. As shown in the machining simulation, this small cutter is able to reach most pocket areas to make cuts, except the narrow area (e.g., the narrow cross line in the letter “N”) and sharp corners. CNC sequences for machining a name plate using Pro/MFG: (a) creating text for volume milling, (b) adding a spline, (c) machining simulation in Vericut, and (d) adding text for an engraving sequence.Īn ⅛ in. workpiece, using both Pro/MFG and Mastercam.įigure 11.40. This tutorial example involves designing and creating a toolpath for machining a customized name plate on a 3 in. This example should help you become more familiar with Pro/MFG, Mastercam and/or CAMWorks. Machining the block using CAMWorks is discussed in Tutorial S4.4.5. Since some information about this example has been discussed in Section 11.3 using Pro/MFG, we will focus more on Mastercam. Three CAM software, Pro/MFG, Mastercam, and CAMWorks are employed for this example. Once you are more familiar with one of these two software tools, you may move to the second tutorial example-block with a sculpture surface-in which both rough and finish cuts are required. In addition, after going through this simple example, you should see the major differences between the two software tools, and hopefully be able to identify a few pros and cons of each. This name plate example involves profile and volume millings and is presented so that you may learn to use Pro/MFG and/or Mastercam in projects P4 and M4, respectively. Kuang-Hua Chang, in e-Design, 2015 11.6.2 Tutorial ExamplesĪ name plate and a sculpture surface example are included in the tutorial lessons. Basically a Final Fantasy BoTW in Structure, but also majoras mask + kingdom hearts and Valkyrie Profile all in one.Ĭlick to shrink.Steam version with these mods: Its Square's most out there and innovative RPG in decades. A beefy CPU and a very fast drive seem to mitigate the behavior quite a bit but it always seems to be there to some degree.Īs an aside, play lightning returns people. Unfortunately, loading boundaries can be close together and if you are running through a city the experience can be, well, XIII-2 esque (which demonstrates similar fixed loading behavior). The only difference is that those console versions have modest frame drops everywhere else, while the PC version will likely be a locked 60 if it's not loading stuff. The game seems to load new parts of the map as you cross particular boundaries - frequently arches and gates in Luxerion and certain stairways in Yusnaan - and the console versions I think still have sizable framerate drops in those particular locations too. The performance issues in cities and whatnot are present in the console versions too. (Maybe you can mod this version though? I dunno) So far, it seems okay, but not really worth getting over the Steam version, since you can mod the latter with a bunch of goodies nowadays like higher-res textures, FMVs, better character models, the original Xbox or PlayStation button prompts, etc. I haven't tried running vanilla Steam FF13 on my current setup before (I always use FF13Fix), so I don't know if they actually fixed the problems or my current machine can just brute force the game without issue or something. I can't really tell if the performance issues have been fixed or not.Hair rendering is the same as the Steam version, so it has some minor issues in spots.The HUD and menu elements are still the same resolution as the original console releases, so they look pixelated at higher resolutions.Someone else will have to take a look at that I can't tell if the FMVs are the same as the Steam version or if they've been replaced with the FMVs from the Xbox backwards compatible versions.This does retain the optional easy difficulty from the Ultimate Hits International and Steam versions, in case there was any concern about that.The controller button prompts are still grey instead of being colored like they were in the Xbox console version. Last but not least, you should also know that SmartScore X2 Pro comes with a built-in sound library. Besides all the advanced features in terms of editing, the tool can also help you print music scores and export them to PDF, MIDI or MusicXML files. Thanks to its efficient recognition engine, you can shortly start editing complex symbols and chord configurations, score structures and even format the page's layout. The application can recognize and playback conductor's scores, band arrangements, PDF scores and transcriptions. No doubt that after a while, SmartScore X2 Pro's menus and features begin to look like familiar territory and you can start taking advantage of what it has to offer. Regardless of your musical knowledge, you should take a few minutes of your time and thoroughly read the online documentation.Ĭomes with a sound library and advanced OCR, editing and exporting features Most of the app's features can be easily accessed from the sidebar and most of the editing work is accomplished with the help of the toolbar.Įven if the initial part of the workflow that implies scanning, loading and the whole recognition process of music scores is fairly intuitive, from here onwards things get a bit difficult. Upon first launching the app, you are met by an overly-crowded main window, with a comprehensive toolbar, a smaller sidebar and a menubar. Now, image replacing the documents with music scores and you surely get what SmartScore X2 Pro is all about.ĭisplays all its important features right in front of you If this is a bit confusing, it surely helps if you think about this app as an OCR (short for Optical Character Recognition) app for texts, namely an app that scans actual paper documents and provides you with their contents in editable text form. Not only this, but the app can also help you edit the music scores, print and export them, as well as playback the described music notes. View the list of sounds included in every edition of SmartScore X2.SmartScore X2 Pro is a complex piece of software created from the ground up to make it as easy as possible for you to transfer the contents of physical music scores to your computer. Garritan sounds are carefully recorded samples of actual musical instruments. Garritan sounds are state-of-art digitally sampled sound libraries that realistically reproduce musical instruments in performance. SmartScore X2 includes a large subset of Garritan jazz, pop and orchestral instrument sounds. Burn voices, parts or entire score to CD audio using Garritan sounds. Open your score in Finale with just one button. Transpose and print directly from SmartScore. Engraver quality output to print, PDF, Finale and MusicXML. Change page layouts, margins, staff widths and distances quickly and easily. Applied changes creates new SmartScore document, leaving original unchanged. Score Structure allows quick removal and re-arrangement of selected parts. Chord configurations can easily be edited, updated and even made invisible.Įxtract parts graphically. Chord symbols are automatically updated when key signatures are transposed. Precision recognition of chord symbols and guitar fret diagrams including symbols written as simple text. Superior recognition and editing of complex symbols such as cross-staff beams and voices, key and time signatures including change-of-key and change-of-time. Extract parts to separate files and burn to audio. Recognize, playback and manipulate conductor's scores, band arrangements, opera, chorale, transcriptions and PDF scores. Download the demo and discover its powers for yourself. SmartScore X2 is an indispensable tool for any arranger, performer, music educator or church minister. A selection of Garritan® band and orchestral instrument sounds is included free so your music will sound rich, nuanced and true-to-life. Process band arrangements, operas, hymns, musicals, instrumental and solo parts as well as full conductor’s scores. SmartScore X2 Pro recognizes scores without any restriction on the number of parts. Imagine a professional-grade scorewriter with the world’s most accurate music-scanning engine at its core, and enough intelligence built in that no degree is required to use it. Before I jump into the iffy, let’s focus on the good. Moss: Book 2 does have subtitles, and I actually found them to be fairly well-done, although, there are various areas in which they are iffy. However, I did feel discomfort after prolonged sessions, and with no way to turn it off -if that’s even possible on VR games- I just had to take frequent breaks. Edges of anything in the game world that aren’t central to my view have strong red and blueish edging making everything feel warped.Īfter some research, the presence of this feature apparently helps players retain their understanding that it isn’t the real world. However, the chromatic abbreviation is heavy. It could be my apparent tolerance to VR at the moment, but I rarely feel queasy when playing. Having everything tucked into this slighter-less-than 180º space does help for seated sessions, and in addition, when moving to new areas, there’s a fade to black transition. What’s presented in front of me is the only playable space with no areas hidden off to the left, right, or behind that can be accessed by Quill. Throughout the game, I feel as if I’m looking down at a tabletop structure. I played Moss: Book 2 cross-legged on my bed, while other players are free to position themselves standing up. There are no options for various positioning setups such as sitting or standing, meaning that there are no complimentary camera features for those who want to limit their physical body movement. After spending a large chunk of time wandering around the level unsuccessfully trying to figure out where to go, I discovered, only through frustrated sword-swinging, that the branches can be slashed. I stumbled across some red thorny branches that caused damage when walked into. In doing so, potential first-time players who may have skipped the title from 2018 are left out and left to figure things out.Īnother example comes down to how studios shouldn’t assume things are clear. This tells me that Ployarc was only thinking about introducing new features to players from the existing title. Later in the game, I unlock the ability to grow climbable foliage and walkable bridges and a pop-up window pauses the game to teach me the feature. That’s not to say that the game has no tutorials at all. Moss: Book 2 could have implemented prompts in the same style as subtitles, having them appear in the visual and actionable space. Instead, players should be guided, even if that’s only for the starting sections, or at all times if desired. With no useful guidance, I just wander around spamming buttons until something works, and only then do I understand a successful mechanic.ĭevelopers shouldn’t leave the basic control schemes down to assumptions from a previous title or genre experience. This is terrible for me particularly as I’m a new VR user right now. The game lacks any form of button prompts from the start, having me go by instinct on how other 3D platformer games are designed. There’s a controls menu that details the control scheme, but if I’d not have attempted to pause the game I’d have not seen this screen. One of my frustrations with Moss: Book 2 is how it begins on the assumption that the player has played the first game. Those wanting to remap buttons can’t, and the game requires a DualShock 4 to even start the game due to the lightbar feature. What I see are subtitles, voiceover languages, and volume sliders. For this reason alone we haven’t done our usual Menu Deep Dive feature. It is possible from here to open a menu to see the Settings, but there’s not a whole lot there. I pull and hold the triggers and open the pages. I see a glowing blue orb, my cursor essentially, and I move the controller around physically with motion control, reaching out toward the book. I’m sitting at a desk with a glowing DualShock 4 controller with orange flashing triggers, showing an animation indicating I need to open the book in front of me. Moss: Book 2 does not contain any form of accessibility or settings from start-up, and I was thrown straight into the intro which is an interactive title screen. Since then, things have changed, and so I was excited to jump into Moss: Book 2 on the PS5 and check out what’s in store for accessibility. That representation, even as a rusty British Sign Language user had me wanting a VR headset, but I never made the plunge. My first introduction to Moss on PS VR was when the videos of Quill, the protagonist of the game, doing American Sign Language were doing the rounds. |
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